狗身上起红疙瘩怎么办

{"263071":{"id":263071,"case_id":31496,"user_id":1000004,"to_user_id":1836796,"type":3,"content":"您好，处方已经开。可以参照进行购买使用，因为平台这边只能整瓶出售，所以部分药物可以考虑在线下医院进行购买。\n然后也一定要定期做好去除，因为怀疑他们是寄生虫感染引起的，所以说需要考虑半个月，给他们使用一次体外驱虫药。后面再考虑一个月使用一次进行预防。","media":{"images":{},"videos":{},"business_params":{"prescription_id":106044}},"is_doctor":1,"status":1,"created_at":"2022-03-17 08:55:46","show_rx":true,"rx_info":{"id":106044,"rx_no":2.02203170854025e+24,"user_id":1836796,"doctor_user_id":1000004,"is_independent":0,"case_id":2662252,"pet_info":{"pet_id":280062,"pet_name":"西高地比熊串","pet_nickname":"咪咪","pet_gender":2,"pet_birth":"0-0","pet_weight":8,"pet_vaccination_status":0,"pet_in_insect_repellent_status":0,"pet_out_insect_repellent_status":1,"pet_age_format":"1个月内"},"diagnose":"寄生虫性皮炎","signature":"","deadline":null,"status":1,"send_status":1,"use_status":0,"created_at":"2022-03-17 08:54:02","updated_at":"2022-03-17 08:55:46","deleted_at":null,"from_source":"online","template_id":0,"drug_data":{"0":{"id":13431,"prescription_id":106044,"doctor_user_id":1000004,"product_id":911,"product_sku_id":952,"dose":1,"dose_unit":"片","use_method":"口服","frequency":"每天2次","days":7,"number":1,"remark":"","created_at":"2022-03-17 08:54:02","updated_at":"2022-03-17 08:54:02","product_info":{"id":911,"hash_id":"kAW7LMp6KJ4BVDnv","class_ids":{"0":1},"category_ids":{"11":172},"is_drugstore":1,"is_prescription":1,"drug_instruction_id":127,"sell_point":"爱波克马来酸奥拉替尼片3.6mg×100片\/瓶","title":"辉瑞爱波克马来酸奥拉替尼片3.6mg×100片\/瓶","recommend_reason":{"0":"用于控制过敏性皮炎引发的瘙痒","1":"控制1岁以上犬只的异位性皮炎"},"baike_guide_text":"","baike_article_hash_id":"","advword":"过敏性皮炎,瘙痒,异位性皮炎,爱波克,奥拉替尼","spec_data":{"1":{"name":"规格","option_data":{"0":{"name":"100粒瓶装"}}}},"cover":"https:\/\/cdn.moguvet.com\/shop\/2022\/01\/862f094a8b8317351824fcea5236f319.jpeg","images":{},"attr_data":{},"content":"","supplier_id":1,"transport_id":1,"min_price":1288,"max_price":1288,"sale_count":0,"tags":"","sort":0,"status":1,"delete_status":0,"created_at":"2022-01-25 13:36:08","updated_at":"2023-06-21 11:56:13","ins":{"id":127,"hash_id":"","class_ids":"[\u00221\u0022]","title":"","common_name":"马来酸奥拉替尼片","trade_name":"爱波克","en_name":"apoquel（oclacitinibtablet）","brand_name":"辉瑞","is_prescription":1,"cover":"\/drug\/2020\/11\/a5be1d99e437054b94f19c39af520048.JPG","specification":"3.6mg×100片\/瓶","reference_price":2500,"component":"马来酸奥拉替尼","indication":"用于控制过敏性皮炎引发的瘙痒以及控制1岁以上犬只的异位性皮炎。","usage_dosage":"以奥拉替尼计，0.4-0.6mg\/kg体重，口服，每日2次，连用14天，然后每日1次维持治疗，可拌食或直接喂食。","contraindication":"1.十二月龄以下犬只禁用；\n2.严重感染的犬只禁用；\n3.繁殖用种公犬及妊娠期、哺乳期的母犬禁用；","adverse_reaction":"1.用于治疗异位性皮炎，长期持续给药可能发生腹泻、呕吐、厌食、嗜睡等不良反应。会导致白细胞系和血清球蛋白数量下降，胆固醇和脂肪酶含量有所升高但均值仍在正常范围内，在使用本品的第14天，平均淋巴细胞数量会短暂升高。\n2.用于治疗过敏性皮炎引发的瘙痒，长期持续给药可能发生腹泻、呕吐、厌食、嗜睡、烦渴等不良反应。白细胞系数量会有轻微上升，但仍在正常范围之内。在使用本品的第7天，平均淋巴细胞数量升高，但在无间断使用本品的临床试验结束之时又恢复到预处理水平。临床试验的30天内，没有发生任何致死和不良反应。","attention":"1.本品与糖皮质激素、环孢菌素或者其他免疫抑制剂的联用未经评估\n2.本品可能会增加传染病的易感性，包括蠕形螨以及恶性肿瘤。\n3.本品不可人用，请将本品放到儿童接触不到的地方，只能用于犬。\n4.接触过药片后请立即洗手。万一发生意外的眼睛接触，应立即用大量的清水或盐水冲洗至少15分钟，然后就医。\n5.如果不慎吞下，请立即就医。","interaction":"","approval_no":"（2019）外兽药证字25号","storage_method":"20℃-25℃室温下储存，可允许偏差范围为15℃-40℃。","validity":"2年","manufacturer":"辉瑞意大利阿斯科利制药厂","status":1,"created_at":"2020-11-30 23:16:11","updated_at":"2020-11-30 23:16:11"}},"product_sku_info":{"id":952,"product_id":911,"title":"辉瑞爱波克马来酸奥拉替尼片3.6mg×100片\/瓶","advword":null,"price":1288,"market_price":1899,"cost_price":0,"stock":100,"stock_alarm":10,"spec_data":{"1":{"name":"规格","option":"100粒瓶装"}},"cover":null,"thumb":"","sale_count":0,"status":1,"delete_status":0,"cloud_repo_id":0,"cloud_repo_goods_id":"","sort":1,"created_at":"2022-01-25 13:36:08","updated_at":"2023-06-21 11:56:13"}},"1":{"id":13432,"prescription_id":106044,"doctor_user_id":1000004,"product_id":785,"product_sku_id":827,"dose":1,"dose_unit":"ml","use_method":"外喷","frequency":"每天2次","days":7,"number":1,"remark":"","created_at":"2022-03-17 08:54:02","updated_at":"2022-03-17 08:54:02","product_info":{"id":785,"hash_id":"L6mEd3xG0ypVGQ2W","class_ids":{"0":1,"1":2},"category_ids":{"0":169},"is_drugstore":1,"is_prescription":0,"drug_instruction_id":8,"sell_point":"复合溶菌酶消毒喷剂30ml","title":"可鲁复合溶菌酶消毒喷剂 30ml\/瓶\/盒","recommend_reason":{"0":"动物的皮肤和粘膜消毒"},"baike_guide_text":"","baike_article_hash_id":"","advword":"皮肤病,细菌感染,外伤","spec_data":{"1":{"name":"规格","option_data":{"0":{"name":"30ml"}}}},"cover":"https:\/\/cdn.moguvet.com\/shop\/2023\/03\/b5035dcc45faa6fabd47b50a77ad04ce.png","images":{},"attr_data":{},"content":"","supplier_id":1,"transport_id":1,"min_price":49,"max_price":49,"sale_count":283,"tags":"","sort":0,"status":0,"delete_status":0,"created_at":"2021-12-20 17:27:19","updated_at":"2024-07-30 10:22:33","ins":{"id":8,"hash_id":"","class_ids":"[\u00221\u0022,\u00222\u0022]","title":"","common_name":"复合溶菌酶消毒喷剂","trade_name":"可鲁喷剂","en_name":"Compound Lysozgme Disinfectant Spray","brand_name":"可鲁","is_prescription":0,"cover":"\/drug\/2020\/10\/c143288e0ecd853448e37d453dc4965e.png","specification":"30ml\/瓶\/盒","reference_price":75,"component":"溶葡萄球菌酶，溶菌酶，醋酸氯已定","indication":"动物的皮肤和粘膜消毒。","usage_dosage":"1.采用本品均匀喷洒于需消毒部位或医用棉球蘸涂,作用5分钟;\n2.或用本品浸湿无菌纱布后湿敷需消毒部位,作用5分钟。","contraindication":"","adverse_reaction":"","attention":"本品不能与双氧水、高锰酸钾、碘制剂等氧化性物质配伍或合用。","interaction":"本品不能与双氧水、高锰酸钾、碘制剂等氧化性物质配伍或合用。","approval_no":"","storage_method":"置于阴凉干燥处保存","validity":"2年","manufacturer":"昆山博青生物科技有限公司","status":1,"created_at":"2020-10-26 15:58:22","updated_at":"2020-10-26 16:06:46"}},"product_sku_info":{"id":827,"product_id":785,"title":"可鲁复合溶菌酶消毒喷剂 30ml\/瓶\/盒","advword":null,"price":49,"market_price":80,"cost_price":0,"stock":502,"stock_alarm":10,"spec_data":{"1":{"name":"规格","option":"30ml"}},"cover":null,"thumb":"","sale_count":294,"status":0,"delete_status":0,"cloud_repo_id":0,"cloud_repo_goods_id":"","sort":1,"created_at":"2021-12-20 17:27:19","updated_at":"2024-07-30 10:22:33"}},"2":{"id":13433,"prescription_id":106044,"doctor_user_id":1000004,"product_id":717,"product_sku_id":759,"dose":1,"dose_unit":"ml","use_method":"口服","frequency":"每天2次","days":14,"number":1,"remark":"","created_at":"2022-03-17 08:54:02","updated_at":"2022-03-17 08:54:02","product_info":{"id":717,"hash_id":"8jZlKwgZ7wxaOQ9y","class_ids":{"0":1,"1":2,"2":3},"category_ids":{"35":194},"is_drugstore":1,"is_prescription":0,"drug_instruction_id":178,"sell_point":"POG复合维生素B溶液","title":"POG复合维生素B溶液 宠物营养补充剂 70ml\/瓶","recommend_reason":{"0":"防治多发性神经炎、消化障碍、癞皮病、口腔炎等","1":"犬猫补血生血、保肝解毒、增强食欲和免疫力、增强机体抵抗力"},"baike_guide_text":"","baike_article_hash_id":"","advword":"B族维生素缺乏,生血,保肝,增强抵抗力","spec_data":{"1":{"name":"规格","option_data":{"0":{"name":"70ml"}}}},"cover":"https:\/\/cdn.moguvet.com\/shop\/2021\/12\/188c431ee66d89012a6328277bf6353c.jpeg","images":{},"attr_data":{},"content":"","supplier_id":1,"transport_id":1,"min_price":88,"max_price":88,"sale_count":586,"tags":"","sort":0,"status":1,"delete_status":0,"created_at":"2021-12-16 16:12:50","updated_at":"2024-11-22 09:22:26","ins":{"id":178,"hash_id":"","class_ids":"[\u00221\u0022,\u00222\u0022]","title":"POG复合维生素B溶液 宠物营养补充剂70ml\/瓶","common_name":"宠物营养补充剂","trade_name":"复合维生素B溶液","en_name":"Compound Vitamin B Solution","brand_name":"POG","is_prescription":0,"cover":"\/drug\/2021\/03\/39f4ff3ed1df89f92164f0a2fb30ccd2.jpg","specification":"70ml\/瓶","reference_price":148,"component":"维生素B1、维生素B2、维生素B6、烟酰胺、 泛酸钙、 维生素B12、锌、铁、芦荟胶、枸杞子。","indication":"养护肝脏，加强红细胞的发育和成熟，使肌体造血机能处于正常状态减少恶性贫血;维护神经系统健康。\n维生素B12:参与制造骨髓红细胞，减少恶性贫血。芦荟:有减少不适情况的发生、加强内脏功能的作用。\n构杞子:有减少脂肪的沉积、加强新细胞生长的作用。铁:铁是血红蛋白的重要部分，铁可以加强机体的功能。\n菊花黄酮:加强内脏对有害物的排泄。","usage_dosage":"犬猫体重3-4kg，喂服1ml\/次或遵医嘱。本品口服，直接喂服或者兑在水中饮用，一日2次(早晚各1次)，用前请摇匀。","contraindication":"","adverse_reaction":"","attention":"喂服前,请将本品摇匀。按滴管标准使用剂量。","interaction":"","approval_no":"","storage_method":"贮存在干燥、避光、遮风、清洁的环境","validity":"24个月","manufacturer":"广西雄邦生物工程有限公司","status":1,"created_at":"2021-03-22 15:14:06","updated_at":"2024-03-08 16:37:39"}},"product_sku_info":{"id":759,"product_id":717,"title":"POG复合维生素B溶液 宠物营养补充剂70ml\/瓶","advword":null,"price":88,"market_price":108,"cost_price":0,"stock":214,"stock_alarm":10,"spec_data":{"1":{"name":"规格","option":"70ml"}},"cover":null,"thumb":"","sale_count":603,"status":1,"delete_status":0,"cloud_repo_id":0,"cloud_repo_goods_id":"","sort":1,"created_at":"2021-12-16 16:12:50","updated_at":"2024-11-21 22:33:29"}}},"drug_data_bak":{"0":{"id":13431,"prescription_id":106044,"doctor_user_id":1000004,"product_id":911,"product_sku_id":952,"dose":1,"dose_unit":"片","use_method":"口服","frequency":"每天2次","days":7,"number":1,"remark":"","created_at":"2022-03-17 08:54:02","updated_at":"2022-03-17 08:54:02","product_info":{"id":911,"hash_id":"kAW7LMp6KJ4BVDnv","class_ids":{"0":1},"category_ids":{"11":172},"is_drugstore":1,"is_prescription":1,"drug_instruction_id":127,"sell_point":"爱波克马来酸奥拉替尼片3.6mg×100片\/瓶","title":"辉瑞爱波克马来酸奥拉替尼片3.6mg×100片\/瓶","recommend_reason":{"0":"用于控制过敏性皮炎引发的瘙痒","1":"控制1岁以上犬只的异位性皮炎"},"baike_guide_text":"","baike_article_hash_id":"","advword":"过敏性皮炎,瘙痒,异位性皮炎,爱波克,奥拉替尼","spec_data":{"1":{"name":"规格","option_data":{"0":{"name":"100粒瓶装"}}}},"cover":"https:\/\/cdn.moguvet.com\/shop\/2022\/01\/862f094a8b8317351824fcea5236f319.jpeg","images":{},"attr_data":{},"content":"","supplier_id":1,"transport_id":1,"min_price":1288,"max_price":1288,"sale_count":0,"tags":"","sort":0,"status":1,"delete_status":0,"created_at":"2022-01-25 13:36:08","updated_at":"2023-06-21 11:56:13","ins":{"id":127,"hash_id":"","class_ids":"[\u00221\u0022]","title":"","common_name":"马来酸奥拉替尼片","trade_name":"爱波克","en_name":"apoquel（oclacitinibtablet）","brand_name":"辉瑞","is_prescription":1,"cover":"\/drug\/2020\/11\/a5be1d99e437054b94f19c39af520048.JPG","specification":"3.6mg×100片\/瓶","reference_price":2500,"component":"马来酸奥拉替尼","indication":"用于控制过敏性皮炎引发的瘙痒以及控制1岁以上犬只的异位性皮炎。","usage_dosage":"以奥拉替尼计，0.4-0.6mg\/kg体重，口服，每日2次，连用14天，然后每日1次维持治疗，可拌食或直接喂食。","contraindication":"1.十二月龄以下犬只禁用；\n2.严重感染的犬只禁用；\n3.繁殖用种公犬及妊娠期、哺乳期的母犬禁用；","adverse_reaction":"1.用于治疗异位性皮炎，长期持续给药可能发生腹泻、呕吐、厌食、嗜睡等不良反应。会导致白细胞系和血清球蛋白数量下降，胆固醇和脂肪酶含量有所升高但均值仍在正常范围内，在使用本品的第14天，平均淋巴细胞数量会短暂升高。\n2.用于治疗过敏性皮炎引发的瘙痒，长期持续给药可能发生腹泻、呕吐、厌食、嗜睡、烦渴等不良反应。白细胞系数量会有轻微上升，但仍在正常范围之内。在使用本品的第7天，平均淋巴细胞数量升高，但在无间断使用本品的临床试验结束之时又恢复到预处理水平。临床试验的30天内，没有发生任何致死和不良反应。","attention":"1.本品与糖皮质激素、环孢菌素或者其他免疫抑制剂的联用未经评估\n2.本品可能会增加传染病的易感性，包括蠕形螨以及恶性肿瘤。\n3.本品不可人用，请将本品放到儿童接触不到的地方，只能用于犬。\n4.接触过药片后请立即洗手。万一发生意外的眼睛接触，应立即用大量的清水或盐水冲洗至少15分钟，然后就医。\n5.如果不慎吞下，请立即就医。","interaction":"","approval_no":"（2019）外兽药证字25号","storage_method":"20℃-25℃室温下储存，可允许偏差范围为15℃-40℃。","validity":"2年","manufacturer":"辉瑞意大利阿斯科利制药厂","status":1,"created_at":"2020-11-30 23:16:11","updated_at":"2020-11-30 23:16:11"}},"product_sku_info":{"id":952,"product_id":911,"title":"辉瑞爱波克马来酸奥拉替尼片3.6mg×100片\/瓶","advword":null,"price":1288,"market_price":1899,"cost_price":0,"stock":100,"stock_alarm":10,"spec_data":{"1":{"name":"规格","option":"100粒瓶装"}},"cover":null,"thumb":"","sale_count":0,"status":1,"delete_status":0,"cloud_repo_id":0,"cloud_repo_goods_id":"","sort":1,"created_at":"2022-01-25 13:36:08","updated_at":"2023-06-21 11:56:13"}},"1":{"id":13432,"prescription_id":106044,"doctor_user_id":1000004,"product_id":785,"product_sku_id":827,"dose":1,"dose_unit":"ml","use_method":"外喷","frequency":"每天2次","days":7,"number":1,"remark":"","created_at":"2022-03-17 08:54:02","updated_at":"2022-03-17 08:54:02","product_info":{"id":785,"hash_id":"L6mEd3xG0ypVGQ2W","class_ids":{"0":1,"1":2},"category_ids":{"0":169},"is_drugstore":1,"is_prescription":0,"drug_instruction_id":8,"sell_point":"复合溶菌酶消毒喷剂30ml","title":"可鲁复合溶菌酶消毒喷剂 30ml\/瓶\/盒","recommend_reason":{"0":"动物的皮肤和粘膜消毒"},"baike_guide_text":"","baike_article_hash_id":"","advword":"皮肤病,细菌感染,外伤","spec_data":{"1":{"name":"规格","option_data":{"0":{"name":"30ml"}}}},"cover":"https:\/\/cdn.moguvet.com\/shop\/2023\/03\/b5035dcc45faa6fabd47b50a77ad04ce.png","images":{},"attr_data":{},"content":"","supplier_id":1,"transport_id":1,"min_price":49,"max_price":49,"sale_count":283,"tags":"","sort":0,"status":0,"delete_status":0,"created_at":"2021-12-20 17:27:19","updated_at":"2024-07-30 10:22:33","ins":{"id":8,"hash_id":"","class_ids":"[\u00221\u0022,\u00222\u0022]","title":"","common_name":"复合溶菌酶消毒喷剂","trade_name":"可鲁喷剂","en_name":"Compound Lysozgme Disinfectant Spray","brand_name":"可鲁","is_prescription":0,"cover":"\/drug\/2020\/10\/c143288e0ecd853448e37d453dc4965e.png","specification":"30ml\/瓶\/盒","reference_price":75,"component":"溶葡萄球菌酶，溶菌酶，醋酸氯已定","indication":"动物的皮肤和粘膜消毒。","usage_dosage":"1.采用本品均匀喷洒于需消毒部位或医用棉球蘸涂,作用5分钟;\n2.或用本品浸湿无菌纱布后湿敷需消毒部位,作用5分钟。","contraindication":"","adverse_reaction":"","attention":"本品不能与双氧水、高锰酸钾、碘制剂等氧化性物质配伍或合用。","interaction":"本品不能与双氧水、高锰酸钾、碘制剂等氧化性物质配伍或合用。","approval_no":"","storage_method":"置于阴凉干燥处保存","validity":"2年","manufacturer":"昆山博青生物科技有限公司","status":1,"created_at":"2020-10-26 15:58:22","updated_at":"2020-10-26 16:06:46"}},"product_sku_info":{"id":827,"product_id":785,"title":"可鲁复合溶菌酶消毒喷剂 30ml\/瓶\/盒","advword":null,"price":49,"market_price":80,"cost_price":0,"stock":502,"stock_alarm":10,"spec_data":{"1":{"name":"规格","option":"30ml"}},"cover":null,"thumb":"","sale_count":294,"status":0,"delete_status":0,"cloud_repo_id":0,"cloud_repo_goods_id":"","sort":1,"created_at":"2021-12-20 17:27:19","updated_at":"2024-07-30 10:22:33"}},"2":{"id":13433,"prescription_id":106044,"doctor_user_id":1000004,"product_id":717,"product_sku_id":759,"dose":1,"dose_unit":"ml","use_method":"口服","frequency":"每天2次","days":14,"number":1,"remark":"","created_at":"2022-03-17 08:54:02","updated_at":"2022-03-17 08:54:02","product_info":{"id":717,"hash_id":"8jZlKwgZ7wxaOQ9y","class_ids":{"0":1,"1":2,"2":3},"category_ids":{"35":194},"is_drugstore":1,"is_prescription":0,"drug_instruction_id":178,"sell_point":"POG复合维生素B溶液","title":"POG复合维生素B溶液 宠物营养补充剂 70ml\/瓶","recommend_reason":{"0":"防治多发性神经炎、消化障碍、癞皮病、口腔炎等","1":"犬猫补血生血、保肝解毒、增强食欲和免疫力、增强机体抵抗力"},"baike_guide_text":"","baike_article_hash_id":"","advword":"B族维生素缺乏,生血,保肝,增强抵抗力","spec_data":{"1":{"name":"规格","option_data":{"0":{"name":"70ml"}}}},"cover":"https:\/\/cdn.moguvet.com\/shop\/2021\/12\/188c431ee66d89012a6328277bf6353c.jpeg","images":{},"attr_data":{},"content":"","supplier_id":1,"transport_id":1,"min_price":88,"max_price":88,"sale_count":586,"tags":"","sort":0,"status":1,"delete_status":0,"created_at":"2021-12-16 16:12:50","updated_at":"2024-11-22 09:22:26","ins":{"id":178,"hash_id":"","class_ids":"[\u00221\u0022,\u00222\u0022]","title":"POG复合维生素B溶液 宠物营养补充剂70ml\/瓶","common_name":"宠物营养补充剂","trade_name":"复合维生素B溶液","en_name":"Compound Vitamin B Solution","brand_name":"POG","is_prescription":0,"cover":"\/drug\/2021\/03\/39f4ff3ed1df89f92164f0a2fb30ccd2.jpg","specification":"70ml\/瓶","reference_price":148,"component":"维生素B1、维生素B2、维生素B6、烟酰胺、 泛酸钙、 维生素B12、锌、铁、芦荟胶、枸杞子。","indication":"养护肝脏，加强红细胞的发育和成熟，使肌体造血机能处于正常状态减少恶性贫血;维护神经系统健康。\n维生素B12:参与制造骨髓红细胞，减少恶性贫血。芦荟:有减少不适情况的发生、加强内脏功能的作用。\n构杞子:有减少脂肪的沉积、加强新细胞生长的作用。铁:铁是血红蛋白的重要部分，铁可以加强机体的功能。\n菊花黄酮:加强内脏对有害物的排泄。","usage_dosage":"犬猫体重3-4kg，喂服1ml\/次或遵医嘱。本品口服，直接喂服或者兑在水中饮用，一日2次(早晚各1次)，用前请摇匀。","contraindication":"","adverse_reaction":"","attention":"喂服前,请将本品摇匀。按滴管标准使用剂量。","interaction":"","approval_no":"","storage_method":"贮存在干燥、避光、遮风、清洁的环境","validity":"24个月","manufacturer":"广西雄邦生物工程有限公司","status":1,"created_at":"2021-03-22 15:14:06","updated_at":"2024-03-08 16:37:39"}},"product_sku_info":{"id":759,"product_id":717,"title":"POG复合维生素B溶液 宠物营养补充剂70ml\/瓶","advword":null,"price":88,"market_price":108,"cost_price":0,"stock":214,"stock_alarm":10,"spec_data":{"1":{"name":"规格","option":"70ml"}},"cover":null,"thumb":"","sale_count":603,"status":1,"delete_status":0,"cloud_repo_id":0,"cloud_repo_goods_id":"","sort":1,"created_at":"2021-12-16 16:12:50","updated_at":"2024-11-21 22:33:29"}}}}}}